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Commun Biol ; 4(1): 35, 2021 01 04.
Artículo en Inglés | MEDLINE | ID: covidwho-1065967

RESUMEN

Coronavirus disease 2019 (COVID-19) is a global pandemic posing significant health risks. The diagnostic test sensitivity of COVID-19 is limited due to irregularities in specimen handling. We propose a deep learning framework that identifies COVID-19 from medical images as an auxiliary testing method to improve diagnostic sensitivity. We use pseudo-coloring methods and a platform for annotating X-ray and computed tomography images to train the convolutional neural network, which achieves a performance similar to that of experts and provides high scores for multiple statistical indices (F1 scores > 96.72% (0.9307, 0.9890) and specificity >99.33% (0.9792, 1.0000)). Heatmaps are used to visualize the salient features extracted by the neural network. The neural network-based regression provides strong correlations between the lesion areas in the images and five clinical indicators, resulting in high accuracy of the classification framework. The proposed method represents a potential computer-aided diagnosis method for COVID-19 in clinical practice.


Asunto(s)
COVID-19/diagnóstico , Aprendizaje Profundo , Redes Neurales de la Computación , Interpretación de Imagen Radiográfica Asistida por Computador/métodos , SARS-CoV-2/aislamiento & purificación , Tomografía Computarizada por Rayos X/métodos , Algoritmos , COVID-19/epidemiología , COVID-19/virología , Humanos , Reacción en Cadena de la Polimerasa de Transcriptasa Inversa , SARS-CoV-2/genética , SARS-CoV-2/fisiología , Sensibilidad y Especificidad
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